Symptoms & Treatments

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Niamh's Journey

  • Phenobarbital (Phenobarbitone)
  • Potassium bromide
  • Prednisolone (steroid)
  • Pyrodoxine (Vitamin B6)
  • Sodium Valporate (Epilim)
  • Stiripentol (Diacomit)
  • Tiagabine (Gabitril)
  • Topiramate (Topomax)
  • Valproic Acid (Depakene)
  • Vigabatrin, (Sabril)
  • Zonisamide (Zonegran)

The best reported combination of drugs in controlling seizures in children with MPEI appears to be slightly different with each child however to date, Keppra and Topirimate have been reported to work the best for children in our support group.

The only drug that our group have reported that made their children's seizures notably worse was Lamotrigine (Lamictal).

Most drugs tried, have either not made any change to the seizures, or any initial positive effects were short lived (a few days up to max 2 weeks).

Ketogenic Diet